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Researchers use epigenetics to discover processes leading to acute myeloid leukemia

Scientists at University of California, Santa Barbara (UCSB) have learned more about the mutation in DNA that leads to the development of acute myeloid leukemia (AML). When the UCSB researchers learned of a study reported in the New England Journal of Medicine that found it was a mutation in the enzyme DNA (cytosine-5)-methyltransferase 3A (DNMT3A) that caused AML, they decided to study the mutation at the cellular level using epigenetics, which studies changes in gene expression not related ...

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